Our bodies contain many unique physiologic systems whose sole purpose would be to maintain an internal balance called homeostasis. We know the pancreas releases insulin to balance sugar levels between the bloodstream and cells. The thyroid gland releases thyroid hormone, which regulates vital bodily functions associated with metabolism, body temperature and a lot more. Simply put, the body are working constantly to stay balanced in response to our external environment.
In the pursuit to understand how THC causes its popular intoxicating effects, scientists learned that we now have one more regulatory physiologic system, referred to as endocannabinoid system (ECS), whose role is to maintain homeostasis of the messages sent between our cells. Further research shows that sickness, inflammation, and injury will trigger the ECS to adopt action, attempting to reset our internal environment returning to homeostasis. This technique has been identified as being protective and necessary for life. What if we might target this method to stop illness and sustain better health?
Endocannabinoids, sometimes called our “inner cannabis,” are synthesized at will from healthy causes of dietary fat. Cannabinoid receptors sit on the membranes of cells in particular parts of your brain and body, namely areas inside the brain that control pain, memory, emotion, motor control, nausea, and appetite, and also the gut, immunity mechanism, and peripheral nervous system. When there is a trigger which induces an imbalance, like an injury or illness, endocannabinoids are released, acting as “keys” that bind towards the receptors, which work as “locks” on our cells. Once the receptor is activated, a chemical reaction occurs within the cell, telling the cell to alter its message.
ECS functioning depends upon many factors, including genetics, age, levels of stress, diet, and overall amount of health. There might be variants inside the genes that code for that ECS which can lead to propensities beyond doubt conditions, including ADHD and PTSD. Additionally, chronic illness, chronic stress and chronic sleep deprivation may lead to depletion in the endocannabinoids. These disruptions within the normal functioning of the ECS interfere with being able to regulate cellular imbalances and achieve homeostasis.
In 2004, Ethan Russo, a neurologist and research scientist, published Clinical endocannabinoids Deficiency (CECD): Can this idea explain therapeutic advantages of cannabis in migraine, fibromyalgia, irritable bowel syndrome and other treatment-resistant conditions? inside the journal Neuroendocrinology Letters. Russo theorized that particular people who have the listed conditions responded to cannabis-based treatments because they had endocannabinoid deficiencies that allowed the condition to manifest in the first place.
Subsequent reports have demonstrated that endocannabinoid deficiency plays a role in autoimmune diseases, epilepsy, complex regional pain syndrome, cardiovascular disease, depression, anxiety, schizophrenia, multiple sclerosis, nausea, Huntington’s disease, Parkinson’s disease, menstrual symptoms, failure to thrive in newborns, and other difficult-to-treat conditions.
The cannabis plant produces over 100 phytocannabinoids, including tetrahydrocannabinol (THC) and cannabidiol (CBD). These compounds mimic the endocannabinoids by interacting with the ECS and restoring homeostasis. Instead of wait until illness is found, there are numerous approaches to take better care of your ECS, that can give it time to function properly, avoid deficiencies and sustain homeostasis.
It’s common knowledge which a healthy, balanced eating habits are essential for emotional and physical well-being. Our bodies rely on our diet to create the right amount of endocannabinoids to function at optimal capacity. Cannabinoids are synthesized from your essential fatty acids in our diets and require a specific balance of omega-6 and omega-3 to be produced in the best quantities.
For maximum bioavailability, the optimal ratio of omega-6 to omega-3 essential fatty acids from food is between 5:1 and 1:1, the low the better for anyone with chronic illness. Western diets routinely include ratios of 20:1, mainly as a result of overconsumption of omega-6 essential fatty acids which originate from vegetable oils in numerous packaged foods. Western diets with higher ratios of omega-6 to omega-3 essential fatty acids results in a reduction of endocannabinoids, resulting in the lack of ability to maintain homeostasis.
Another thing that promotes well-being from the ECS is aerobic fitness exercise. Animal studies are convinced that voluntary wheel running increases cannabinoid receptors within the brain and increases the sensitivity of the receptors to endocannabinoids. Human studies show that exercise like running, biking and hiking enhance endocannabinoid levels inside the bloodstream. In fact, endocannabinoids are probably in charge of the phenomenon described as the “runner’s high.”
Probiotics could also help the ECS. Lactobacillus acidophilus, a probiotic bacteria found in fermented foods including yogurt and sauerkraut, was proven to induce the expression of cannabinoid receptors within the gut, promoting intestinal homeostasis.
Both acupuncture and osteopathic manipulation boost the ECS. Yoga and meditation elicit the “relaxation response,” a physiological wjeflf phenomenon whereby anybody can consciously participate in behavior that promotes physical and mental wellness; although no studies have been done to date, many experts suspect these stress management modalities improve the ECS thereby promoting homeostasis.
Lastly, have you thought about the ability of cannabis to avoid illness? Plant cannabinoids are well-regarded as safe and to have anti-inflammatory, antioxidant and neuroprotective properties. In cases of endocannabinoid deficiency, cannabis use may be the correcting compound, eliminating the symptoms of the condition. Regular cannabis use can decrease chronic inflammation and buildup of toxins, both of which are thought to be the root factors behind many conditions, including autoimmune and neurodegenerative disorders.